Kratom is an herb that has attracted the attention of healthcare regulators as well as the general public. However, it would be fun to know the exact phytochemistry of this South-Asian herb that has been notoriously controversial. So, if you are interested more in understanding this herb and its make, let us get straight to it before you order Kratom online.
PhytoChemical Chemistry of Kratom Alkaloids
Plants, just like all the living beings on Earth, are created with naturally occurring chemical compounds. These chemicals are termed phytochemicals. Among these, alkaloids make up a major part of the chemical compounds in plants. These alkaloids can be found in a range of plants that include ergot, poppy, & mitragynine speciosa (Kratom).
Of all the phytochemicals present in Kratom, alkaloids are kind of special. As you search for Kratom online, remember that the alkaloids have strong effects, so caution should always be practiced. Depending on the Kratom variant, the alkaloid’s effects can vary physiologically all the way to psychologically.
The diversity and potency of the alkaloids in Kratom have called for extensive research in the clinical domain. Keep in mind that two different alkaloids have different effects depending on the source it is extracted from. For example, if the source is yellow Kratom or red Kratom, the effects would differ when compared to green or white Kratom. So, this could be a big deciding factor the next time you order Kratom online.
Initially, scientists believed that alkaloids were products only in plants. However, the latest research has determined that this chemical compound can be found in some animal species as well.
Commonly Occurring Kratom Alkaloid
Two of the major and abundantly occurring alkaloids in Kratom are 7-hydroxy-mitragynine and mitragynine. They are mostly responsible for the effects experienced by people that use them. These 2 alkaloids present in Kratom are considered selective in terms of action. They act on the MORs or µ-subtype receptors for opioids. Again, keep in mind that different plants feature different concentrations of alkaloids. Apart from this, certain types of alkaloids can be found only in 1 or 2 plant species.
When talking about Kratom online, as per research, it has been uncovered that this plant has a minimum of 28 different alkaloids. Among these, the mitragynine & 7-hydroxy mitragynine pack in the most dramatic effects for its users.
Mitragynine:
An abundantly available alkaloid in Kratom, it makes up about 66 percent of the total concentration of alkaloids in this plant. However, this particular concentration isn’t always accurate for all Kratom variants. Further, it can also vary depending on the growing conditions, harvesting time, & kratom strain. Tests conducted on different strains of Kratom samples show that the level of mitragynine is generally higher in the white vein and green vein kratom strains.
However, the level of mitragynine in Kratom is lower in the Malaysian strain. Moreover, it must also be kept in mind that this alkaloid has 3.85 hours of half-life, which could increase or decrease an hour depending on each strain’s biochemistry. So, depending on one’s personal preference, order Kratom online by keeping in mind the mitragynine level in any particular strain.
7-Hydroxymitragynine:
Although the 7-hydroxy mitragynine is an important part of Kratom, it is a rather rarer alkaloid variant that makes up about 2 percent of the total alkaloid composition in the plant. The concentration of 7-hydroxy mitragynine can vary significantly depending on several factors. The highest level of this alkaloid can be found in the red vein kratom. However, keep in mind that this alkaloid has 2.5 hours of half-life that could vary by 0.7 hours or so. Its effect is for less time as compared to mitragynine.
As the kratom plant grows and matures, the alkaloid balance in the same shifts with time. For example, mitragynine levels tend to be highest when this plant is fairly young. However, the same isn’t true for 7-hydroxy mitragynine. It tends to increase only when the plant starts to achieve maturity. This particular gradual shift that happens with the plant causes a noticeable change in the alkaloid level. While these alkaloid levels tend to change, the plant’s leaves’ veins start to see a change in color. In the early stages of plant growth, the veins tend to be white, and slowly they shift towards a greener tint.
Finally, when the Kratom plant becomes completely mature, the veins pack in a red hue.
Conclusion
As of now, only limited studies and research have been conducted on the kratom plant and its chemical content. However, with more and more people starting to notice this herb, researchers are now trying to understand how this plant’s alkaloids work.
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